Autism spectrum disorder (ASD) is diagnosed on the basis of behavioral parameters, yet there are many underlying biomedical factors which can contribute to these symptoms. Therapies directed at these underlying factors may be helpful in decreasing symptoms of autism. For example, recent studies have found chronic inflammation in the brains of children with autism, raising the possibility that treatments directed against inflammation may be helpful.
The Autism Research Institute asked parents to rate the effectiveness of numerous biomedical treatments. As of 2008, over 26,000 parents had evaluated more than 80 interventions. Detoxification was considered helpful by 74% of parents. Other highly rated therapies included gluten/casein-free diet, food allergy treatment, methylcobalamin, and essential fatty acid therapy. It is thought that the earlier treatment is started, the better the results.
Gluten-Free and Casein-Free Preparations
Compromised digestive function, often secondary to inflammation of the bowel, may lead to the absorption of toxins (“leaky gut”). Children can benefit from balanced nutrition, treatment of imbalanced gut flora, and enhancement of immune function.
Many children with autism are zinc deficient. Zinc deficiency affects taste perception and children then become averse to eating certain foods and taking supplements. In this case, transdermal preparations can be very helpful by completely bypassing the oral route of administration. Commonly needed nutrients which can easily be given in a transdermal form include vitamin A, vitamin D, and zinc.
Melatonin appears to be a safe and well-tolerated treatment for insomnia in children with ASD.
J Child Neurol. 2008 May;23(5):482-5.
Detoxification (including chelation)
Ann Neurol 2005;57:67–81
Ann N Y Acad Sci. 2007 Jun;1107:92-103.
Cell Mol Neurobiol. 2004 Apr;24(2):219-41
Neuroendocrinology Letters 2002;23:303-8
Dev Brain Dysfunction 1997;10:40-43
J Inherit Metab Dis.1993;16(4):762-770
J Nutr Env Med 2000;10:25-32
Low Dose Naltrexone (LDN) and Autism
- Hormone Replacement Therapy for Men
- Hormone Replacement Therapy for Women
- Athlete’s Foot
- Chemical Peels
- Diaper Rash/Incontinence
- Head Lice and Scabies
- Molluscum Contagiosum
- Nail Infection/Removal
- Pigmentation Abnormalities
- Plantar Warts/Warts
- Scarring and Keloids
- Topical Anesthetics
- Sun Protection/Photoaged Skin/Wrinkles
- Examples of Compounded Medications
- Pain Management
- Palliative Care
- Sports Medicine
- Veterinary Compounding
- Wound Care
- PHYSICIANS ONLY
- SCHOLARSHIP INFO