Doxycycline Administered in Drinking Water for Treatment of Spiral Bacterial Infection in Birds
Antifungal Therapy for Avian Species
The efficacy of terbinafine has been improved when administered in combination with azoles for treatment of azole resistant oral candidiasis and aspergillosis. Because terbinafine was administered successfully in an African gray parrot at 15 mg/kg every 12 hours for 30 days without adverse effects, it may have potential for use in systemic aspergillosis in these azole-sensitive species. Caution should be used in avian patients with liver or renal disease.
Veterinary Clin North Am Exot Anim Pract. 2003 May;6(2):337-50, vi
Treatment of a Systemic Fungal Infection in a Parrot with Itraconazole Flavored Suspension and Nebulized Clotrimazole
A Solomon Island Eclectus parrot, female aged 1.5 years, presented in a weakened state. Examination and culture revealed a systemic Aspergillus infection. Due to its significant cost as well as concern for the pet, the owner was highly motivated to treat the parrot.
Treatment posed a challenge because the parrot only eats brightly-colored foods, and there was no commercially available clotrimazole solution for nebulization for veterinary use. The veterinarian contacted the local compounding pharmacy to discuss how compounded medications might help solve this therapeutic dilemma. It was decided that an oral suspension flavored with equal parts orange, banana, and strawberry could mask the bitter flavor of itraconazole, and that a customized dosage (20mg/ml) could be compounded for the parrot. The veterinarian also prescribed clotrimazole 1% for nebulization.
The owner administered 0.2ml (4mg) of itraconazole suspension to the bird each day by mouth using an oral syringe. Therapy continued for three months. Clotrimazole 1% solution was nebulized (1ml BID to TID) by placing a pediatric nebulizer mask over the cooperative bird's head. After 30 days, the bird still had a productive cough. Therefore, nebulizer therapy with clotrimazole continued after total resolution of signs and symptoms of infection, for a total of four months (one month after the oral itraconazole was finished).
The parrot fully recovered. This case represented the pharmacy's first attempt at avian therapy, and was 100% successful. The same therapy was used later for another bird that also fully recovered from a systemic Aspergillus infection.
Enrofloxacin in Birds
10th U Wisc Exotic Pet Conf Procd 04:01
Haloperidol for Feather-Plucking and Self-Mutilation
Journal of Small Animal Practice 1993; 34:564-566
Haloperidol for Feather Plucking
Signalment: "Echo", adult male Eclectus Parrot
Chief Complaint: Feather picking of 4-6 years duration
Diagnosis: Previous veterinarian had done numerous tests in 1993 to rule out medical causes of feather picking and the final diagnosis was psychological behavioral feather picking.
Feather Picking: This is a common syndrome in pet "parrot-type" birds that can have medical and/or psychological causes. It is important to rule out all medical causes of this condition before initiating psychotropic drug therapy. It is also important to institute appropriate dietary and environmental changes as well as behavioral therapy along with psychotropic drug use.
Past History and Medications: Echo first started picking at his feathers in 1991. By November of 1994 he had pulled out all his feathers except those which he could not reach on his head. In December of 1994, Echo's previous veterinarian started him on naltrexone (dose unknown) for behavioral feather picking. He failed to respond to this drug and was placed in an Elizabethan collar on 4/20/95 to prevent further plucking. The author first saw this patient on 1/10/97. He had been wearing the collar almost constantly since 4/95 and all his feathers were in place (but ragged and unkempt looking) except under the collar. Anytime the collar was removed the patient would rip his feathers out. The owners wished to try Prozac? for Echo's problem but since this author has had little success with Prozac?, we started trials on other drugs. Along with changes in diet and environment and behavioral exercises, we started Echo on Aventyl? elixir at 1/4 teaspoon per 4 ounces of drinking water to be replaced with fresh twice daily. We also initiated every other daily misting of the feathers with a dilute Aloe and Penetran? suspension. By 3/8/97, Echo was still plucking too many feathers when the collar was removed. To his Aventyl? therapy, we added naltrexone compounded to 5 mg/ml in a strawberry flavored base, 0.16 ml by mouth twice daily. By 3/20/97 he was still plucking badly when the collar was removed.
The Aventyl and naltrexone were discontinued and we did a brief trial on diazepam 2 mg per 4 ounces of drinking water. The diazepam is not meant to sedate and the owner was instructed to increase the dose to a maximum of 10 mg per 4 ounces of water if feather plucking continued but only if no sedation was noted. The diazepam produced no change in behavior and caused too much sedation for Echo. On 4/10/97 we began a trial on haloperidol 2 mg/ml at .015 ml by mouth once daily. The owners were instructed that they could increase the dose to maximum of .06cc of 2 mg/ml haloperidol twice daily. By 5/7/97, Echo's owners reported that they were giving .075 cc of 2 mg/ml haloperidol twice daily and he seemed to be responding nicely. On 5/17/97 the haloperidol was refilled and compounded to 1 mg/ml to facilitate easier measuring. As of 9/2/98, Echo is receiving haloperidol 0.15 mg by mouth twice daily. This is a higher dose than I have seen published in the literature but the owners are pleased with Echo's condition and do not wish to try a lower dose or even possibly wean him off the haloperidol. Echo is not experiencing any noticeable side effects from his haloperidol therapy. Currently, Echo never wears his Elizabethan collar and is totally feathered in except for his neck. I believe that 2 years of constant pressure from the collar has caused atrophy of the feather follicles around the neck.
- Hormone Replacement Therapy for Men
- Hormone Replacement Therapy for Women
- Athlete’s Foot
- Chemical Peels
- Diaper Rash/Incontinence
- Head Lice and Scabies
- Molluscum Contagiosum
- Nail Infection/Removal
- Pigmentation Abnormalities
- Plantar Warts/Warts
- Scarring and Keloids
- Topical Anesthetics
- Sun Protection/Photoaged Skin/Wrinkles
- Examples of Compounded Medications
- Pain Management
- Palliative Care
- Sports Medicine
- Veterinary Compounding
- Wound Care
- PHYSICIANS ONLY
- SCHOLARSHIP INFO